Open Access in Latin America is the predominant publishing model because governments have committed with the diffusion of science outputs since 20th century, therefore it is publicly funded. Science policies have considered the relevance of publishing journals as one of the main strategies to spread the research results, however there are several challenges journals face in terms of infrastructure, professionalization of editors, funds, among others. This talk will provide some data on the main concerns that publishers have been discussed during my experience in workshops and meetings on DOAJ, that has committed to improve quality of journals published in the Global South.